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Induction of IFNα or IL-12 depends on differentiation of THP-1 cells in dengue infections without and with antibody enhancement

BACKGROUND: Appropriate induction of the early Th1 cytokine IL-12 is a critical defense directed against viral infection. We have previously shown that different viruses elicited either IL-12 or IFNα dependent Th1 reactions. Using dengue-2 virus, we sought to explore how dengue-2 induced IL-12 or IF...

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Detalles Bibliográficos
Autores principales:	Chen, Rong-Fu, Wang, Lin, Cheng, Jiin-Tsuey, Yang, Kuender D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575308/ https://www.ncbi.nlm.nih.gov/pubmed/23216989 http://dx.doi.org/10.1186/1471-2334-12-340

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