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PKCδ as a Regulator for TGFβ1-Induced α-SMA Production in a Murine Nonalcoholic Steatohepatitis Model

The precise mechanism of TGFβ1 signaling in the progression of non-alcoholic steatohepatitis (NASH) has remained unclear. In particular, a potential regulatory mechanism by which PKCδ affects profibrogenic gene expression had never been explored. In this study, therefore, the role of PKCδ in TGFβ1 m...

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Detalles Bibliográficos
Autores principales: Lee, Su Jin, Kang, Jeong Han, Choi, Soo Young, Suk, Ki Tae, Kim, Dong Joon, Kwon, Oh-Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575342/
https://www.ncbi.nlm.nih.gov/pubmed/23441159
http://dx.doi.org/10.1371/journal.pone.0055979