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Increased Matrix Metalloproteinase (MMPs) Levels Do Not Predict Disease Severity or Progression in Emphysema

RATIONALE: Though matrix metalloproteinases (MMPs) are critical in the pathogenesis of COPD, their utility as a disease biomarker remains uncertain. This study aimed to determine whether bronchoalveolar lavage (BALF) or plasma MMP measurements correlated with disease severity or functional decline i...

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Detalles Bibliográficos
Autores principales: D’Armiento, Jeanine M., Goldklang, Monica P., Hardigan, Andrew A., Geraghty, Patrick, Roth, Michael D., Connett, John E., Wise, Robert A., Sciurba, Frank C., Scharf, Steven M., Thankachen, Jincy, Islam, Monirul, Ghio, Andrew J., Foronjy, Robert F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575373/
https://www.ncbi.nlm.nih.gov/pubmed/23441181
http://dx.doi.org/10.1371/journal.pone.0056352