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A Remote Cis-Acting Variant at 3q Links Glomerular NCK1 to Diabetic Nephropathy

We have previously reported genetic association of a single nucleotide polymorphism (SNP), rs1866813, at 3q locus with increased risk of diabetic nephropathy (DN). The SNP is located approximately 70 kb downstream of a cluster of four genes. This raises a question how the remote noncoding polymorphi...

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Detalles Bibliográficos
Autores principales: He, Bing, Österholm, Anne-May, Ojala, Juha R. M., Andersson, Ann-Charlotte, Tryggvason, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575385/
https://www.ncbi.nlm.nih.gov/pubmed/23441190
http://dx.doi.org/10.1371/journal.pone.0056414