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Ubiquitous Gasp1 overexpression in mice leads mainly to a hypermuscular phenotype

BACKGROUND: Myostatin, a member of the TGFβ superfamily, is well known as a potent and specific negative regulator of muscle growth. Targeting the myostatin signalling pathway may offer promising therapeutic strategies for the treatment of muscle-wasting disorders. In the last decade, various myosta...

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Detalles Bibliográficos
Autores principales: Monestier, Olivier, Brun, Caroline, Heu, Katy, Passet, Bruno, Malhouroux, Mélanie, Magnol, Laetitia, Vilotte, Jean-Luc, Blanquet, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575399/
https://www.ncbi.nlm.nih.gov/pubmed/23046573
http://dx.doi.org/10.1186/1471-2164-13-541