Genomic EWS-FLI1 Fusion Sequences in Ewing Sarcoma Resemble Breakpoint Characteristics of Immature Lymphoid Malignancies

Chromosomal translocations between the EWS gene and members of the ETS gene family are characteristic molecular features of the Ewing sarcoma. The most common translocation t(11;22)(q24;q12) fuses the EWS gene to FLI1, and is present in 85–90% of Ewing sarcomas. In the present study, a specifically...

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Detalles Bibliográficos
Autores principales: Berger, Manfred, Dirksen, Uta, Braeuninger, Andreas, Koehler, Gabriele, Juergens, Heribert, Krumbholz, Manuela, Metzler, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575406/
https://www.ncbi.nlm.nih.gov/pubmed/23441188
http://dx.doi.org/10.1371/journal.pone.0056408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575406/
https://www.ncbi.nlm.nih.gov/pubmed/23441188
http://dx.doi.org/10.1371/journal.pone.0056408

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