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The Roles of Macrophages and Nitric Oxide in Interleukin-3-Enhanced HSV-Sr39tk-Mediated Prodrug Therapy

The herpes simplex virus thymidine kinase/ganciclovir (HSV-sr39tk/GCV) system is a well-established prodrug system used in cancer gene therapy. However, this system is currently not effective enough to eradicate malignant tumors completely. This study aimed to evaluate whether co-expression of inter...

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Detalles Bibliográficos
Autores principales: Yu, Ching-Fang, Hong, Ji-Hong, Chiang, Chi-Shiun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575414/
https://www.ncbi.nlm.nih.gov/pubmed/23441198
http://dx.doi.org/10.1371/journal.pone.0056508