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Multiple Cationic Amphiphiles Induce a Niemann-Pick C Phenotype and Inhibit Ebola Virus Entry and Infection

Ebola virus (EBOV) is an enveloped RNA virus that causes hemorrhagic fever in humans and non-human primates. Infection requires internalization from the cell surface and trafficking to a late endocytic compartment, where viral fusion occurs, providing a conduit for the viral genome to enter the cyto...

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Detalles Bibliográficos
Autores principales: Shoemaker, Charles J., Schornberg, Kathryn L., Delos, Sue E., Scully, Corinne, Pajouhesh, Hassan, Olinger, Gene G., Johansen, Lisa M., White, Judith M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575416/
https://www.ncbi.nlm.nih.gov/pubmed/23441171
http://dx.doi.org/10.1371/journal.pone.0056265