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The Role of TLR4 in the Paclitaxel Effects on Neuronal Growth In Vitro

Paclitaxel (Pac) is an antitumor agent that is widely used for treatment of solid cancers. While being effective as a chemotherapeutic agent, Pac in high doses is neurotoxic, specifically targeting sensory innervations. In view of these toxic effects associated with conventional chemotherapy, decrea...

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Detalles Bibliográficos
Autores principales: Ustinova, Elena E., Shurin, Galina V., Gutkin, Dmitriy W., Shurin, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575491/
https://www.ncbi.nlm.nih.gov/pubmed/23441224
http://dx.doi.org/10.1371/journal.pone.0056886