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The Role of TLR4 in the Paclitaxel Effects on Neuronal Growth In Vitro
Paclitaxel (Pac) is an antitumor agent that is widely used for treatment of solid cancers. While being effective as a chemotherapeutic agent, Pac in high doses is neurotoxic, specifically targeting sensory innervations. In view of these toxic effects associated with conventional chemotherapy, decrea...
Autores principales: | Ustinova, Elena E., Shurin, Galina V., Gutkin, Dmitriy W., Shurin, Michael R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575491/ https://www.ncbi.nlm.nih.gov/pubmed/23441224 http://dx.doi.org/10.1371/journal.pone.0056886 |
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