Cargando…
Rag GTPases mediate amino acid–dependent recruitment of TFEB and MITF to lysosomes
The mTORC1 complex supports cell growth and proliferation in response to energy levels, growth factors, and nutrients. The Rag guanosine triphosphatases (GTPases) activate mTORC1 in response to amino acids by promoting its redistribution to lysosomes. In this paper, we identify a novel role for Rags...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575543/ https://www.ncbi.nlm.nih.gov/pubmed/23401004 http://dx.doi.org/10.1083/jcb.201209135 |