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SecYEG activates GTPases to drive the completion of cotranslational protein targeting

Signal recognition particle (SRP) and its receptor (SR) comprise a highly conserved cellular machine that cotranslationally targets proteins to a protein-conducting channel, the bacterial SecYEG or eukaryotic Sec61p complex, at the target membrane. Whether SecYEG is a passive recipient of the transl...

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Detalles Bibliográficos
Autores principales: Akopian, David, Dalal, Kush, Shen, Kuang, Duong, Franck, Shan, Shu-ou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575545/
https://www.ncbi.nlm.nih.gov/pubmed/23401005
http://dx.doi.org/10.1083/jcb.201208045