Butein inhibits ethanol-induced activation of liver stellate cells through TGF-β, NFκB, p38, and JNK signaling pathways and inhibition of oxidative stress

BACKGROUND: Butein has been reported to prevent and partly reverse liver fibrosis in vivo; however, the mechanisms of its action are poorly understood. We, therefore, aimed to determine the antifibrotic potential of butein. METHODS: We assessed the influence of the incubation of hepatic stellate cel...

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Detalles Bibliográficos
Autores principales: Szuster-Ciesielska, Agnieszka, Mizerska-Dudka, Magdalena, Daniluk, Jadwiga, Kandefer-Szerszeń, Martyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2012
Materias:
Original Article—Liver, Pancreas, and Biliary Tract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575555/
https://www.ncbi.nlm.nih.gov/pubmed/22722906
http://dx.doi.org/10.1007/s00535-012-0619-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575555/
https://www.ncbi.nlm.nih.gov/pubmed/22722906
http://dx.doi.org/10.1007/s00535-012-0619-7

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