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Butein inhibits ethanol-induced activation of liver stellate cells through TGF-β, NFκB, p38, and JNK signaling pathways and inhibition of oxidative stress
BACKGROUND: Butein has been reported to prevent and partly reverse liver fibrosis in vivo; however, the mechanisms of its action are poorly understood. We, therefore, aimed to determine the antifibrotic potential of butein. METHODS: We assessed the influence of the incubation of hepatic stellate cel...
Autores principales: | Szuster-Ciesielska, Agnieszka, Mizerska-Dudka, Magdalena, Daniluk, Jadwiga, Kandefer-Szerszeń, Martyna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Japan
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575555/ https://www.ncbi.nlm.nih.gov/pubmed/22722906 http://dx.doi.org/10.1007/s00535-012-0619-7 |
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