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Vector-Mediated Selective Expression of Lethal Factor, a Toxic Element of Bacillus Anthracis, Damages A549 Cells via Inhibition of MAPK and AKT Pathways

Lethal factor (LF), a major toxic element of Bacillus anthracis combined with its protective antigen (PA), enters the cells through the cytomembrane receptors and causes damage to the host cells, thereby leading to septicemia, toxemia, and meningitis with high mortality. LF has been identified as a...

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Detalles Bibliográficos
Autores principales: Zhuo, Wenlei, Tao, Guangli, Zhang, Liang, Chen, Zhengtang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575624/
https://www.ncbi.nlm.nih.gov/pubmed/23423542
http://dx.doi.org/10.7150/ijms.5570