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Vector-Mediated Selective Expression of Lethal Factor, a Toxic Element of Bacillus Anthracis, Damages A549 Cells via Inhibition of MAPK and AKT Pathways
Lethal factor (LF), a major toxic element of Bacillus anthracis combined with its protective antigen (PA), enters the cells through the cytomembrane receptors and causes damage to the host cells, thereby leading to septicemia, toxemia, and meningitis with high mortality. LF has been identified as a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575624/ https://www.ncbi.nlm.nih.gov/pubmed/23423542 http://dx.doi.org/10.7150/ijms.5570 |