Cargando…

Capicua regulates proliferation and survival of RB-deficient cells in Drosophila

Mutations in rbf1, the Drosophila homologue of the RB tumour suppressor gene, generate defects in cell cycle control, cell death, and differentiation during development. Previous studies have established that EGFR/Ras activity is an important determinant of proliferation and survival in rbf1 mutant...

Descripción completa

Detalles Bibliográficos
Autores principales: Krivy, Kate, Bradley-Gill, Mary-Rose, Moon, Nam-Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575652/
https://www.ncbi.nlm.nih.gov/pubmed/23429853
http://dx.doi.org/10.1242/bio.20123277