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Functional characterization of motif sequences under purifying selection

Diverse life forms are driven by the evolution of gene regulatory programs including changes in regulator proteins and cis-regulatory elements. Alterations of cis-regulatory elements are likely to dominate the evolution of the gene regulatory networks, as they are subjected to smaller selective cons...

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Detalles Bibliográficos
Autores principales: Chen, De-Hua, Chang, Andrew Ying-Fei, Liao, Ben-Yang, Yeang, Chen-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575792/
https://www.ncbi.nlm.nih.gov/pubmed/23303791
http://dx.doi.org/10.1093/nar/gks1456