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Conformational dynamics of the human propeller telomeric DNA quadruplex on a microsecond time scale

The human telomeric DNA sequence with four repeats can fold into a parallel-stranded propeller-type topology. NMR structures solved under molecular crowding experiments correlate with the crystal structures found with crystal-packing interactions that are effectively equivalent to molecular crowding...

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Detalles Bibliográficos
Autores principales: Islam, Barira, Sgobba, Miriam, Laughton, Charlie, Orozco, Modesto, Sponer, Jiri, Neidle, Stephen, Haider, Shozeb
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575793/
https://www.ncbi.nlm.nih.gov/pubmed/23293000
http://dx.doi.org/10.1093/nar/gks1331