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Rev3, the catalytic subunit of Polζ, is required for maintaining fragile site stability in human cells
It has been long speculated that mammalian Rev3 plays an important, yet unknown role(s) during mammalian development, as deletion of Rev3 causes embryonic lethality in mice, whereas no other translesion DNA synthesis polymerases studied to date are required for mouse embryo development. Here, we rep...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575803/ https://www.ncbi.nlm.nih.gov/pubmed/23303771 http://dx.doi.org/10.1093/nar/gks1442 |