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Rev3, the catalytic subunit of Polζ, is required for maintaining fragile site stability in human cells

It has been long speculated that mammalian Rev3 plays an important, yet unknown role(s) during mammalian development, as deletion of Rev3 causes embryonic lethality in mice, whereas no other translesion DNA synthesis polymerases studied to date are required for mouse embryo development. Here, we rep...

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Detalles Bibliográficos
Autores principales:	Bhat, Audesh, Andersen, Parker L., Qin, Zhoushuai, Xiao, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575803/ https://www.ncbi.nlm.nih.gov/pubmed/23303771 http://dx.doi.org/10.1093/nar/gks1442

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