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Distinct transcriptional regulatory modules underlie STAT3’s cell type-independent and cell type-specific functions

Transcription factors (TFs) regulate gene expression by binding to short DNA sequence motifs, yet their binding specificities alone cannot explain how certain TFs drive a diversity of biological processes. In order to investigate the factors that control the functions of the pleiotropic TF STAT3, we...

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Detalles Bibliográficos
Autores principales: Hutchins, Andrew Paul, Diez, Diego, Takahashi, Yoshiko, Ahmad, Shandar, Jauch, Ralf, Tremblay, Michel Lucien, Miranda-Saavedra, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575808/
https://www.ncbi.nlm.nih.gov/pubmed/23295670
http://dx.doi.org/10.1093/nar/gks1300