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The high kinetic stability of a G-quadruplex limits hnRNP F qRRM3 binding to G-tract RNA

The RNA binding protein heterogeneous nuclear ribonucleoprotein (hnRNP) F is involved in telomeres maintenance and pre-mRNA processing, such as alternative splicing and polyadenylation. It specifically recognizes RNA containing three consecutive guanines (G-tracts) that have the potential to assembl...

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Detalles Bibliográficos
Autores principales: Samatanga, Brighton, Dominguez, Cyril, Jelesarov, Ilian, Allain, Frédéric H.-T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575826/
https://www.ncbi.nlm.nih.gov/pubmed/23275549
http://dx.doi.org/10.1093/nar/gks1289