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Ribonucleotides and manganese ions improve non-homologous end joining by human Polµ

Human DNA polymerase mu (Polμ), a family X member involved in DNA repair, has both template-directed and terminal transferase (template-independent) activities. In addition to their ability to incorporate untemplated nucleotides, another similarity between Polµ and terminal deoxynucleotidyl transfer...

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Detalles Bibliográficos
Autores principales: Martin, Maria Jose, Garcia-Ortiz, Maria V., Esteban, Veronica, Blanco, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575841/
https://www.ncbi.nlm.nih.gov/pubmed/23275568
http://dx.doi.org/10.1093/nar/gks1444