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Space exploration by the promoter of a long human gene during one transcription cycle

An RNA polymerase has been thought to transcribe by seeking out a promoter, initiating and then tracking down the template. We add tumor necrosis factor α to primary human cells, switch on transcription of a 221-kb gene and monitor promoter position during the ensuing transcription cycle (using RNA...

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Detalles Bibliográficos
Autores principales: Larkin, Joshua D., Papantonis, Argyris, Cook, Peter R., Marenduzzo, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575846/
https://www.ncbi.nlm.nih.gov/pubmed/23303786
http://dx.doi.org/10.1093/nar/gks1441