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A dual-site simultaneous binding mode in the interaction between parallel-stranded G-quadruplex [d(TGGGGT)](4) and cyanine dye 2,2′-diethyl-9-methyl-selenacarbocyanine bromide
G-quadruplexes have attracted growing attention as a potential cancer-associated target for both treatment and detection in recent years. For detection purpose, high specificity is one of the most important factors to be considered in G-quadruplex probe design. It is well known that end stacking and...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575849/ https://www.ncbi.nlm.nih.gov/pubmed/23275573 http://dx.doi.org/10.1093/nar/gks1328 |