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A dual-site simultaneous binding mode in the interaction between parallel-stranded G-quadruplex [d(TGGGGT)](4) and cyanine dye 2,2′-diethyl-9-methyl-selenacarbocyanine bromide

G-quadruplexes have attracted growing attention as a potential cancer-associated target for both treatment and detection in recent years. For detection purpose, high specificity is one of the most important factors to be considered in G-quadruplex probe design. It is well known that end stacking and...

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Detalles Bibliográficos
Autores principales: Gai, Wei, Yang, Qianfan, Xiang, Junfeng, Jiang, Wei, Li, Qian, Sun, Hongxia, Guan, Aijiao, Shang, Qian, Zhang, Hong, Tang, Yalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575849/
https://www.ncbi.nlm.nih.gov/pubmed/23275573
http://dx.doi.org/10.1093/nar/gks1328