Intrathecal Lamotrigine Attenuates Mechanical Allodynia and Suppresses Microglial and Astrocytic Activation in a Rat Model of Spinal Nerve Ligation

PURPOSE: Lamotrigine, a novel anticonvulsant, is a sodium channel blocker that is efficacious in certain forms of neuropathic pain. Recently, microglial and astrocytic activation has been implicated in the development of nerve injury-induced neuropathic pain. We have assessed the effects of continuo...

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Detalles Bibliográficos
Autores principales: Choi, Yun-Sik, Jun, In-Gu, Kim, Sung-Hoon, Park, Jong-Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575973/
https://www.ncbi.nlm.nih.gov/pubmed/23364963
http://dx.doi.org/10.3349/ymj.2013.54.2.321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575973/
https://www.ncbi.nlm.nih.gov/pubmed/23364963
http://dx.doi.org/10.3349/ymj.2013.54.2.321

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