Rapamycin Inhibits Transforming Growth Factor β1-Induced Fibrogenesis in Primary Human Lung Fibroblasts

PURPOSE: The present study was designed to determine whether rapamycin could inhibit transforming growth factor β1 (TGF-β1)-induced fibrogenesis in primary lung fibroblasts, and whether the effect of inhibition would occur through the mammalian target of rapamycin (mTOR) and its downstream p70S6K pa...

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Detalles Bibliográficos
Autores principales: Gao, Yu, Xu, Xuefeng, Ding, Ke, Liang, Yan, Jiang, Dianhua, Dai, Huaping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576000/
https://www.ncbi.nlm.nih.gov/pubmed/23364979
http://dx.doi.org/10.3349/ymj.2013.54.2.437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576000/
https://www.ncbi.nlm.nih.gov/pubmed/23364979
http://dx.doi.org/10.3349/ymj.2013.54.2.437

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