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Rapamycin Inhibits Transforming Growth Factor β1-Induced Fibrogenesis in Primary Human Lung Fibroblasts
PURPOSE: The present study was designed to determine whether rapamycin could inhibit transforming growth factor β1 (TGF-β1)-induced fibrogenesis in primary lung fibroblasts, and whether the effect of inhibition would occur through the mammalian target of rapamycin (mTOR) and its downstream p70S6K pa...
Autores principales: | Gao, Yu, Xu, Xuefeng, Ding, Ke, Liang, Yan, Jiang, Dianhua, Dai, Huaping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Yonsei University College of Medicine
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576000/ https://www.ncbi.nlm.nih.gov/pubmed/23364979 http://dx.doi.org/10.3349/ymj.2013.54.2.437 |
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