Influence of DNA Repair on Nonlinear Dose-Responses for Mutation

Recent evidence has challenged the default assumption that all DNA-reactive alkylating agents exhibit a linear dose-response. Emerging evidence suggests that the model alkylating agents methyl- and ethylmethanesulfonate and methylnitrosourea (MNU) and ethylnitrosourea observe a nonlinear dose-respon...

Descripción completa

Detalles Bibliográficos
Autores principales: Thomas, Adam D., Jenkins, Gareth J. S., Kaina, Bernd, Bodger, Owen G., Tomaszowski, Karl-Heinz, Lewis, Paul D., Doak, Shareen H., Johnson, George E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576011/
https://www.ncbi.nlm.nih.gov/pubmed/23288051
http://dx.doi.org/10.1093/toxsci/kfs341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576011/
https://www.ncbi.nlm.nih.gov/pubmed/23288051
http://dx.doi.org/10.1093/toxsci/kfs341

Ejemplares similares