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Cobalt chloride inhibits tumor formation in osteosarcoma cells through upregulation of HIF-1α
The exact effect of hypoxia on cancer development is controversial. The present study investigates the ability of osteosarcoma to form tumors in the hypoxic microenvironment induced by CoCl(2). MG63 human osteosarcoma cells were cultured with different concentrations (0, 150 and 300 μM) of CoCl(2) f...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576193/ https://www.ncbi.nlm.nih.gov/pubmed/23426939 http://dx.doi.org/10.3892/ol.2013.1127 |