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Upregulation of mesencephalic astrocyte-derived neurotrophic factor in glial cells is associated with ischemia-induced glial activation

BACKGROUND: Mesencephalic astrocyte-derived neurotrophic factor (MANF), a 20 kDa secreted protein, was originally derived from a rat mesencephalic type-1 astrocyte cell line. MANF belongs to a novel evolutionally conserved family of neurotrophic factors along with conserved dopamine neurotrophic fac...

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Detalles Bibliográficos
Autores principales: Shen, Yujun, Sun, Aimin, Wang, Yunhong, Cha, Daqin, Wang, Haiping, Wang, Facai, Feng, Lijie, Fang, Shengyun, Shen, Yuxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576245/
https://www.ncbi.nlm.nih.gov/pubmed/23173607
http://dx.doi.org/10.1186/1742-2094-9-254