The biochemistry of acetaminophen hepatotoxicity and rescue: a mathematical model

BACKGROUND: Acetaminophen (N-acetyl-para-aminophenol) is the most widely used over-the-counter or prescription painkiller in the world. Acetaminophen is metabolized in the liver where a toxic byproduct is produced that can be removed by conjugation with glutathione. Acetaminophen overdoses, either a...

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Detalles Bibliográficos
Autores principales: Ben-Shachar, Rotem, Chen, Yifei, Luo, Shishi, Hartman, Catherine, Reed, Michael, Nijhout, H Frederik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576299/
https://www.ncbi.nlm.nih.gov/pubmed/23249634
http://dx.doi.org/10.1186/1742-4682-9-55

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576299/
https://www.ncbi.nlm.nih.gov/pubmed/23249634
http://dx.doi.org/10.1186/1742-4682-9-55

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