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50nm-Scale Localization of Single Unmodified, Isotopically Enriched, Proteins in Cells
Imaging single proteins within cells is challenging if the possibility of artefacts due to tagging or to recognition by antibodies is to be avoided. It is generally believed that the biological properties of proteins remain unaltered when (14)N isotopes are replaced with (15)N. (15)N-enriched protei...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576336/ https://www.ncbi.nlm.nih.gov/pubmed/23431383 http://dx.doi.org/10.1371/journal.pone.0056559 |