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Kinase Suppressor of Ras 1 Is Not Required for the Generation of Regulatory and Memory T Cells
The mammalian target of rapamycin (mTOR) kinase is a critical regulator of the differentiation of helper and regulatory CD4+ T cells, as well as memory CD8+ T cells. In this study, we investigated the role of the ERK signaling pathway in regulating mTOR activation in T cells. We showed that activati...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576348/ https://www.ncbi.nlm.nih.gov/pubmed/23431403 http://dx.doi.org/10.1371/journal.pone.0057137 |