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Rac3 induces a molecular pathway triggering breast cancer cell aggressiveness: differences in MDA-MB-231 and MCF-7 breast cancer cell lines

BACKGROUND: Rho GTPases are involved in cellular functions relevant to cancer. The roles of RhoA and Rac1 have already been established. However, the role of Rac3 in cancer aggressiveness is less well understood. METHODS: This work was conducted to analyze the implication of Rac3 in the aggressivene...

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Detalles Bibliográficos
Autores principales: Gest, Caroline, Joimel, Ulrich, Huang, Limin, Pritchard, Linda-Louise, Petit, Alexandre, Dulong, Charlène, Buquet, Catherine, Hu, Chao-Quan, Mirshahi, Pezhman, Laurent, Marc, Fauvel-Lafève, Françoise, Cazin, Lionel, Vannier, Jean-Pierre, Lu, He, Soria, Jeannette, Li, Hong, Varin, Rémi, Soria, Claudine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576359/
https://www.ncbi.nlm.nih.gov/pubmed/23388133
http://dx.doi.org/10.1186/1471-2407-13-63