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GSTP1 negatively regulates Stat3 activation in epidermal growth factor signaling

Glutathione S-transferases (GSTs) are the enzymes that defend cells against the damage mediated by oxidant and electrophilic carcinogens. GSTπ (GSTP1) is a member of the GST family and the hypermethylation GSTP1 CpG island DNA is detected in human hepatocellular carcinoma (HCC) tissues, which contri...

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Detalles Bibliográficos
Autores principales: KOU, XIANJUAN, CHEN, NING, FENG, ZHIYONG, LUO, LAN, YIN, ZHIMIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576364/
https://www.ncbi.nlm.nih.gov/pubmed/23426146
http://dx.doi.org/10.3892/ol.2012.1098