The hyaluronan synthesis inhibitor 4-methylumbelliferone exhibits antitumor effects against mesenchymal-like canine mammary tumor cells

Hyaluronan (HA), a principal constituent of the extracellular matrix (ECM), mediates growth and metastasis of tumor cells. The role of HA in the epithelial-mesenchymal transition (EMT) is well known, and increased ECM remodeling is observed in mesenchymal-like cells. The HA synthesis inhibitor 4-met...

Descripción completa

Detalles Bibliográficos
Autores principales: SAITO, TERUYOSHI, DAI, TAMURA, ASANO, RYUJI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576365/
https://www.ncbi.nlm.nih.gov/pubmed/23426189
http://dx.doi.org/10.3892/ol.2013.1124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576365/
https://www.ncbi.nlm.nih.gov/pubmed/23426189
http://dx.doi.org/10.3892/ol.2013.1124

Ejemplares similares