Functional Pathway Analysis Using SCNP of FLT3 Receptor Pathway Deregulation in AML Provides Prognostic Information Independent from Mutational Status

FMS-like tyrosine kinase 3 receptor (FLT3) internal tandem duplication (ITD) mutations result in constitutive activation of this receptor and have been shown to increase the risk of relapse in patients with acute myeloid leukemia (AML); however, substantial heterogeneity in clinical outcomes still e...

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Detalles Bibliográficos
Autores principales: Cesano, Alessandra, Putta, Santosh, Rosen, David B., Cohen, Aileen C., Gayko, Urte, Mathi, Kavita, Woronicz, John, Hawtin, Rachael E., Cripe, Larry, Sun, Zhuoxin, Tallman, Martin S., Paietta, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576376/
https://www.ncbi.nlm.nih.gov/pubmed/23431389
http://dx.doi.org/10.1371/journal.pone.0056714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576376/
https://www.ncbi.nlm.nih.gov/pubmed/23431389
http://dx.doi.org/10.1371/journal.pone.0056714

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