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Functional Pathway Analysis Using SCNP of FLT3 Receptor Pathway Deregulation in AML Provides Prognostic Information Independent from Mutational Status
FMS-like tyrosine kinase 3 receptor (FLT3) internal tandem duplication (ITD) mutations result in constitutive activation of this receptor and have been shown to increase the risk of relapse in patients with acute myeloid leukemia (AML); however, substantial heterogeneity in clinical outcomes still e...
Autores principales: | Cesano, Alessandra, Putta, Santosh, Rosen, David B., Cohen, Aileen C., Gayko, Urte, Mathi, Kavita, Woronicz, John, Hawtin, Rachael E., Cripe, Larry, Sun, Zhuoxin, Tallman, Martin S., Paietta, Elisabeth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576376/ https://www.ncbi.nlm.nih.gov/pubmed/23431389 http://dx.doi.org/10.1371/journal.pone.0056714 |
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