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Regression of Albuminuria and Hypertension and Arrest of Severe Renal Injury by a Losartan-Hydrochlorothiazide Association in a Model of Very Advanced Nephropathy

Treatments that effectively prevent chronic kidney disease (CKD) when initiated early often yield disappointing results when started at more advanced phases. We examined the long-term evolution of renal injury in the 5/6 nephrectomy model (Nx) and the effect of an association between an AT-1 recepto...

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Detalles Bibliográficos
Autores principales: Arias, Simone Costa Alarcon, Valente, Carla Perez, Machado, Flavia Gomes, Fanelli, Camilla, Origassa, Clarice Silvia Taemi, de Brito, Thales, Camara, Niels Olsen Saraiva, Malheiros, Denise Maria Avancini Costa, Zatz, Roberto, Fujihara, Clarice Kazue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576388/
https://www.ncbi.nlm.nih.gov/pubmed/23431367
http://dx.doi.org/10.1371/journal.pone.0056215