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Regression of Albuminuria and Hypertension and Arrest of Severe Renal Injury by a Losartan-Hydrochlorothiazide Association in a Model of Very Advanced Nephropathy
Treatments that effectively prevent chronic kidney disease (CKD) when initiated early often yield disappointing results when started at more advanced phases. We examined the long-term evolution of renal injury in the 5/6 nephrectomy model (Nx) and the effect of an association between an AT-1 recepto...
Autores principales: | Arias, Simone Costa Alarcon, Valente, Carla Perez, Machado, Flavia Gomes, Fanelli, Camilla, Origassa, Clarice Silvia Taemi, de Brito, Thales, Camara, Niels Olsen Saraiva, Malheiros, Denise Maria Avancini Costa, Zatz, Roberto, Fujihara, Clarice Kazue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576388/ https://www.ncbi.nlm.nih.gov/pubmed/23431367 http://dx.doi.org/10.1371/journal.pone.0056215 |
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