N332-Directed Broadly Neutralizing Antibodies Use Diverse Modes of HIV-1 Recognition: Inferences from Heavy-Light Chain Complementation of Function

Dozens of broadly neutralizing HIV-1 antibodies have been isolated in the last few years from the sera of HIV-1-infected individuals. Only a limited number of regions on the HIV-1 spike, however, are recognized by these antibodies. One of these regions (N332) is characterized by an N-linked glycan a...

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Detalles Bibliográficos
Autores principales: Pancera, Marie, Yang, Yongping, Louder, Mark K., Gorman, Jason, Lu, Gabriel, McLellan, Jason S., Stuckey, Jonathan, Zhu, Jiang, Burton, Dennis R., Koff, Wayne C., Mascola, John R., Kwong, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576407/
https://www.ncbi.nlm.nih.gov/pubmed/23431362
http://dx.doi.org/10.1371/journal.pone.0055701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576407/
https://www.ncbi.nlm.nih.gov/pubmed/23431362
http://dx.doi.org/10.1371/journal.pone.0055701

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