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N332-Directed Broadly Neutralizing Antibodies Use Diverse Modes of HIV-1 Recognition: Inferences from Heavy-Light Chain Complementation of Function
Dozens of broadly neutralizing HIV-1 antibodies have been isolated in the last few years from the sera of HIV-1-infected individuals. Only a limited number of regions on the HIV-1 spike, however, are recognized by these antibodies. One of these regions (N332) is characterized by an N-linked glycan a...
Autores principales: | Pancera, Marie, Yang, Yongping, Louder, Mark K., Gorman, Jason, Lu, Gabriel, McLellan, Jason S., Stuckey, Jonathan, Zhu, Jiang, Burton, Dennis R., Koff, Wayne C., Mascola, John R., Kwong, Peter D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576407/ https://www.ncbi.nlm.nih.gov/pubmed/23431362 http://dx.doi.org/10.1371/journal.pone.0055701 |
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