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Intrinsic immunity against retrotransposons by APOBEC cytidine deaminases

Over 40% of the human genome is recognizable as having been derived from ancient retroelements, transported by an intracellular copy-and-paste process involving an RNA intermediate, with an additional few percent classified as DNA transposable elements. Endogenous retroviruses are long terminal repe...

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Detalles Bibliográficos
Autores principales: Koito, Atsushi, Ikeda, Terumasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576619/
https://www.ncbi.nlm.nih.gov/pubmed/23431045
http://dx.doi.org/10.3389/fmicb.2013.00028