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Mitotic spindle scaling during Xenopus development by kif2a and importin α

Early development of many animals is characterized by rapid cleavages that dramatically decrease cell size, but how the mitotic spindle adapts to changing cell dimensions is not understood. To identify mechanisms that scale the spindle during Xenopus laevis embryogenesis, we established an in vitro...

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Detalles Bibliográficos
Autores principales: Wilbur, Jeremy D, Heald, Rebecca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576809/
https://www.ncbi.nlm.nih.gov/pubmed/23425906
http://dx.doi.org/10.7554/eLife.00290