Opposition between PKC isoforms regulates histone deimination and neutrophil extracellular chromatin release

In response to inflammation, neutrophils deiminate histones and externalize chromatin. Neutrophil extracellular traps (NETs) are an innate immune defense mechanism, yet NETs also may aggravate chronic inflammatory and autoimmune disorders. Activation of peptidylarginine deiminase 4 (PAD4) is associa...

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Detalles Bibliográficos
Autores principales: Neeli, Indira, Radic, Marko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576869/
https://www.ncbi.nlm.nih.gov/pubmed/23430963
http://dx.doi.org/10.3389/fimmu.2013.00038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576869/
https://www.ncbi.nlm.nih.gov/pubmed/23430963
http://dx.doi.org/10.3389/fimmu.2013.00038

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