Intra-articular methotrexate associated to lipid nanoemulsions: anti-inflammatory effect upon antigen-induced arthritis

OBJECTIVE: Commercial methotrexate formulations (MTX) have poor anti-inflammatory action for intra-articular treatment of rheumatoid arthritis. Our aim was to investigate whether an association between methotrexate and lipidic nanoemulsions (LDE) could improve MTX intra-articular action. METHODS: Fo...

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Detalles Bibliográficos
Autores principales: Mello, Suzana BV, Tavares, Elaine R, Bulgarelli, Adriana, Bonfá, Eloisa, Maranhão, Raul C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576886/
https://www.ncbi.nlm.nih.gov/pubmed/23439784
http://dx.doi.org/10.2147/IJN.S29392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576886/
https://www.ncbi.nlm.nih.gov/pubmed/23439784
http://dx.doi.org/10.2147/IJN.S29392

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