Microregional antitumor activity of a small-molecule hypoxia-inducible factor 1 inhibitor

Hypoxia-inducible factor 1 (HIF-1) activates the transcription of genes that play crucial roles in the adaptation of cancer cells to hypoxia. HIF-1α overexpression has been associated with poor prognosis in patients with various types of cancer. Here, we describe ER-400583-00 as a novel HIF-1 inhibi...

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Detalles Bibliográficos
Autores principales: OKAMOTO, KIYOSHI, ITO, DAISUKE, MIYAZAKI, KAZUKI, WATANABE, SAORI, TOHYAMA, OSAMU, YOKOI, AKIRA, OZAWA, YOICHI, ASANO, MAKOTO, KAWAMURA, TAKANORI, YAMANE, YOSHINOBU, NAGAO, SATOSHI, FUNASAKA, SETSUO, KAMATA, JUNICHI, KOTAKE, YOSHIHIKO, AOKI, MIKA, TSUKAHARA, NAOKO, MIZUI, YOSHIHARU, TANAKA, ISAO, SAWADA, KOHEI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577141/
https://www.ncbi.nlm.nih.gov/pubmed/22211243
http://dx.doi.org/10.3892/ijmm.2011.875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577141/
https://www.ncbi.nlm.nih.gov/pubmed/22211243
http://dx.doi.org/10.3892/ijmm.2011.875

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