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Inhibition airway remodeling and transforming growth factor-β1/Smad signaling pathway by astragalus extract in asthmatic mice

Airway remodeling is characterized by airway wall thickening, subepithelial fibrosis, increased smooth muscle mass, angiogenesis and increased mucous glands, which can lead to a chronic and obstinate asthma with pulmonary function depression. In the present study, we investigated whether the astraga...

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Detalles Bibliográficos
Autores principales: QU, ZHENG-HAI, YANG, ZHAO-CHUAN, CHEN, LEI, LV, ZHI-DONG, YI, MING-JI, RAN, NI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577142/
https://www.ncbi.nlm.nih.gov/pubmed/22200784
http://dx.doi.org/10.3892/ijmm.2011.868