Epigenetic reactivation of estrogen receptor-α (ERα) by genistein enhances hormonal therapy sensitivity in ERα-negative breast cancer

BACKGROUND: Estrogen receptor-α (ERα)-negative breast cancer is clinically aggressive and normally does not respond to conventional estrogen target-directed therapies. The soybean isoflavone, genistein (GE), has been shown to prevent and inhibit breast cancer and recent studies have suggested that G...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yuanyuan, Meeran, Syed M, Patel, Shweta N, Chen, Huaping, Hardy, Tabitha M, Tollefsbol, Trygve O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577460/
https://www.ncbi.nlm.nih.gov/pubmed/23379261
http://dx.doi.org/10.1186/1476-4598-12-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577460/
https://www.ncbi.nlm.nih.gov/pubmed/23379261
http://dx.doi.org/10.1186/1476-4598-12-9

Ejemplares similares